The annual loupes ceremony is set for Wednesday, September 18, 2024. We hope you can join us in person or via zoom as we present the second year residents with their loupes, named for members of the Naffziger Society. Names of the residents and honorees will be announced soon, please check back here for details!
The J. Engelbert Dunphy Resident Research Symposium is an annual event which showcases the research of residents, fellows and medical students in the Department of Surgery, and honors the life and accomplishments of J. Engelbert Dunphy, M.D., a legendary surgeon and a former chair of the UCSF Department of Surgery.
Wednesday, May 8, 2024 7:00 AM – 4:15 PM Location: CS-0101, Parnassus campus This event will also be live streamed here.
1. How did you get interested in your research topic?
I have always found aortic aneurysms to be fascinating and often dramatic. Their slow development over time allows for a clear window for treatment, yet operative management ca be very challenging and high-risk. Since my first days in the operating room with vascular surgery, I have wondered why we haven’t been able to develop a therapeutic to stop or reverse aortic aneurysm development. This ultimately has led me to want to better understand the role that the immune system plays in aneurysm development with the goal of identifying a target for a novel therapeutic.
2. How did you select your research mentorship team?
My research interests aligned well with the mission of Dr. Adam Oskowitz’s basic science laboratory. It was natural to work with him and our interests organically aligned. We then identified Dr. Alexis Combes as a collaborator given his laboratory’s extensive experience with single cell RNA sequencing and access to cutting edge spatial transcriptomics platforms.
3. How will you incorporate your research into your future career goals?
I hope to bridge the gap between patients, clinical data, and the laboratory. As a surgeon, I hope to be uniquely positioned to build trust with my patients, recruit them to participate in translational research studies, and increase our ability to build biobanks of blood and tissue samples to be studied.
1. How did you get interested in your research topic?
Early in my residency with a particular interest in reconstructive surgery, I started looking into outcomes of our breast reconstruction patients at UCSF. I noticed that despite many surgeons routinely giving extended courses of oral antibiotics to post-mastectomy patients after implant-based breast reconstruction, our data showed relatively high infection rates, as did the literature. It made us wonder about the utility of antibiotics then in truly protecting against infections, or potentially breeding resistance for more devastating, untreatable implant complications. The field of microbiome science is a novel way to study this problem which had never been seen before in plastic surgery, and our group hypothesized there could be individualized differences in the breast and gut microbiome of certain patients that could predispose one to develop an infection and/or to benefit from prophylactic antibiotics. Given its broad application in all surgical fields I was extremely interested in helping to carry out our prospective randomized trial looking at the effect of prophylactic antibiotics on a patient’s microbiome, and breast reconstructive outcomes.
Similarly, I wondered about other ways to improve our outcomes, and was curious about the application of topical tranexamic acid (TXA), something that is used frequently off-label in aesthetic surgery and pediatric plastic surgery to decreased bleeding. I think it has the potential, with minimal associated risks, to improve hematoma and seroma outcomes in breast surgery. After systematically reviewing the literature for supporting evidence, I helped start a new trial looking at the use of topical TXA in breast reconstruction patients.
2. How did you select your research mentorship team?
I was fortunate to find an incredibly supportive research mentorship team of amazing female role models. I started working with Dr. Merisa Piper from my intern year with a few clinical outcome projects in breast reconstruction, and those projects looking at our institutional outcomes really served as the foundation for our inquiries on how/what we could do to improve our complication rates. I was then connected with Dr. Laura Esserman as a result of previous microbiome work she had done among breast cancer patients, and she helped foster more creative thinking and design of studies to help solve our clinical problems. Additionally, Dr. Laura Barnes who is a plastic surgery resident one year above me spearheaded the microbiome project from the ground up, inspiring me to continue in her footsteps with this trial, and start another looking at TXA.
3. How will you incorporate your research into your future career goals?
I am interested in academic reconstructive plastic surgery and my dedicated research year in residency helped me develop translational research skills required to ask and answer questions that could affect clinical change, while working with multi-disciplinary groups to solve complex problems in health care. I am excited about the possibilities for microbiome science, and hope to leverage knowledge of this innovative area in my career for improved outcomes in the future.
Scott L. Hansen, MD, FACS, was born in Tacoma, Washington, and spent his childhood in various locations, including North Dakota, Chicago, Wisconsin, and Virginia. After completing high school, he initiated his college journey at Radford University and later transferred to George Mason University upon choosing a Pre-Med major. Dr. Hansen continued his education at Eastern Virginia Medical School.
For his General/Plastic Surgery Training, Dr. Hansen chose UCSF as his destination. During this period, he undertook a significant 3-year NIH sponsored research fellowship with David Young in the SFGH Surgical Laboratory, focusing on the study of wound healing. Following the completion of his Plastic Surgery training, Dr. Hansen pursued a Hand and Microsurgery Fellowship at UCLA.
In 2007, Dr. Hansen returned to UCSF, taking on the pivotal roles of Chief of Plastic Surgery at ZSFG and Chief of Hand Surgery at UCSF. His clinical interests encompass a wide range, including hand and wrist surgery, microsurgery, and the treatment of sports-related injuries. Notably, he serves as the Hand and Wrist Surgeon for the San Francisco Giants baseball team.
Beyond his professional achievements, Dr. Hansen is happily married to Christyna and is a proud parent to four children, consisting of two girls and two boys. During weekends, he can often be found on the sidelines of various sports events, including basketball games, water polo matches, soccer fields, or swim meets.
1. How did you get interested in Plastic and Reconstructive Surgery? I became interested in Plastic Surgery during my first year at Eastern Virginia Medical School (EVMS). I was interested in getting a research project and was paired up with a Plastic Surgeon doing wound healing and microsurgery research. I began shadowing him in the Operating Room and was immediately awestruck with Microsurgical Reconstruction. I was able to observe complex nerve reconstruction with Dr. Julia Terzis who was one of the worlds experts at that time. As it turns out EVMS had an incredibly prestigious Plastic Surgery program in the 90’s thus I was exposed to a wide breath of faculty and diverse cases. I knew then that I wanted to pursue plastic surgery.
2. How were you inspired to train at UCSF and now become the Chief of Plastic Surgery? Who was your primary mentor to achieve that position? When I was at EVMS, one of my mentors- Larry Colen, was a former UCSF Plastic Surgery resident and suggested that I do a Sub-I at UCSF. I came to UCSF in 1996 for a Sub-I and was extremely impressed with the training program. At that time Stephen Mathes was the Chief of Plastic Surgery and would become my mentor. Dr. Mathes was a giant in the field of Plastic Surgery and inspired me to become an academic Plastic Surgeon. I was the first resident at UCSF to match into Plastic Surgery as an intern. Up until me, UCSF only trained fellows who had completed General Surgery first. After return from my fellowship at UCLA in 2007, I was further mentored by Dr. William Hoffman who helped me rise to be the current Chief of Plastic Surgery as of 2/2/2024.
3. What are your current research interests and what are some topical areas future Plastic surgeons should be investigate? Me and my research team study disparities in health care, specifically the care of patients with hand infections who are marginally housed or homeless. We are doing a number of studies though our outpatient clinic at ZSFG (OASIS Clinic). Other areas of interest include sports-related injuries, upper extremity trauma, complex spine reconstruction, groin reconstruction and the surgical management of suppurative hidradenitis. Our team collaborates with faulty in Dermatology, Vascular Surgery and Orthopaedic/Neurosurgical Spine surgery. There many areas of Plastic Surgery to explore. These include global health initiatives, lymphatic surgery, robotic plastic surgery and gender-affirming surgery.
The PCSA 95th Annual Meeting was held on February 9-12, 2024, at the Westin Rancho Mirage Golf Resort & Spa. UCSF help an alumni dinner during the weekend and few Naffziger members were in attendance.